It is an appeal for vigilance launched on Tuesday 14 February by the National Agency for Medicines Safety (Ansm). In fact, hormonal IUDs containing a high dose of levonorgestrel slightly increase the risk of depressive disorders in patients, according to a study conducted in cooperation with health insurance.
Hormonal IUD: More frequent use of antidepressants
To make this observation, the Epi-Phare group examined data on health insurance reimbursements for 91,472 women aged 13 to 40. The target? Observe their consumption of psychotropic drugs (antidepressants, anxiolytics and hypnotics) in the two years following the installation of a hormonal IUD, dosed at 52 mg or 19.5 mg of levonorgestrel.
Self the study found no increased use of anxiolytics or hypnoticshowever, he confirmed it people with a 52 mg IUD are 13% more likely to use antidepressants within two years of installation.
The affected IUDs are Mirena and Donasert.
“Improve the exchange with the professional”
Asked by AFP extensionIsabelle Yoldjian, medical director of the ANSM, wants to be reassuring: ” The risks are low to very low. This information does not allow to determine a course of action, but to provide additional information and improve the exchange between the doctor and the patient. “.
However, it is clear that women continue to suffer the adverse effects of hormonal contraception (and the associated mental burden). As a male contraceptive pill is tested without side effects, will we soon finally be at peace?
If you experience any of these side effects after inserting an IUD, talk to your obstetrician, general practitioner, midwife, or pharmacist:
- Fever, severe headaches, migraines;
- Mood swings, depression;
- unusual vaginal discharge, severe or persistent pain in the lower abdomen, painful intercourse;
- Persistent bleeding outside the rules.
Cover image: Unsplash / Reproductive Health Supplies Coalition
Source: Madmoizelle

Mary Crossley is an author at “The Fashion Vibes”. She is a seasoned journalist who is dedicated to delivering the latest news to her readers. With a keen sense of what’s important, Mary covers a wide range of topics, from politics to lifestyle and everything in between.