Coleen Rooney pays heartfelt tribute to late sister Rosie on the 10th anniversary of her death after battling Rett Syndrome

Coleen Rooney pays heartfelt tribute to late sister Rosie on the 10th anniversary of her death after battling Rett Syndrome

Coleen Rooney has paid heartfelt tribute to her late sister Rosie on the tenth anniversary of her death.

Rosie died in 2013 after a lifelong battle with Rett syndrome, a rare brain disorder that causes severe disability.

WAG, 36, who is married to Wayne Rooney, shared a sweet family photo with Rosie in her mother’s arms on Instagram on Thursday.

‘We all love you and miss you’: Coleen Rooney paid heartfelt tribute to her late sister Rosie by sharing a sweet family photo on the 10th anniversary of her death

Coleen captioned the post, “10 years today… We all love and miss you Rosie Mc,” and her followers shared their condolences in the comments section.

Rosie bravely fought a lifelong battle with Rett Syndrome – a rare brain disorder that affects physical movement and can cause very different symptoms in each individual.

Rosie was originally taken in as a foster child by Coleen’s parents, Masons Tony, and Colette, a former childminder, when she was two years old.

Although they knew she was disabled, they did not know the full extent of her condition, which is incurable.

Coleen captioned the post,

Coleen captioned the post, “10 years today… We all love and miss you Rosie Mc,” and her followers shared their condolences in the comments section

Sweet: Rosie was originally taken in as a foster child by Coleen's parents, Masons Tony and Colette (pictured), a former childminder, when she was two years old

Sweet: Rosie was originally taken in as a foster child by Coleen’s parents, Masons Tony and Colette (pictured), a former childminder, when she was two years old

In an exclusive for The Mail on Sunday in 2006, Coleen wrote: “When Rosie first arrived she could crawl and although she couldn’t use her hands as much, she could handle toys on her playmat and eat.

“But over time she stopped crawling and lost her hands. Then she started having trouble swallowing her food.

“It took Rosie about a year to be diagnosed and looking back I can see how much mum pushed to find out what was wrong with her and try to do what was best for her.”

Coleen idolized her adoptive sister and chose Rosie as her bridesmaid when she married Wayne in 2008.

An honour: Coleen idolized her adoptive sister and chose Rosie as her bridesmaid when she married Wayne in 2008

An honour: Coleen idolized her adoptive sister and chose Rosie as her bridesmaid when she married Wayne in 2008

In a statement released shortly after their deaths, Tony and Colette wrote: “Sadly our special angel Rosie, our beloved daughter and sister, returned to Heaven at 2.50am this morning to be surrounded by her loving family.

Rosie was only 14 years old and she fought a lifelong battle with Rett Syndrome. Throughout her life, she brought so much love and happiness to our entire family and everyone who knew and met her.

“She was such a strong little girl and an inspiration to us all. We will forever cherish the memories we shared and the love she showed us every day of her life. As a family we are sad but blessed to have her in our lives.”

Coleen was holidaying in Barbados with her younger brothers, Joe and Anthony, but cut the trip short when she learned that Rosie’s condition had worsened.

WHAT IS RETT SYNDROME? THE NEUROLOGICAL DISORDER THAT CHILDREN CAN’T TALK, EAT, WALK, TALK AND HOLD BREATH

One in 12,000 children are born with Rett syndrome, but few people have heard of it.

The genetic condition almost exclusively affects women, causing them to deteriorate neurologically and physically.

The course of the disease can be roughly divided into four stages.

In the first stage, around six to 18 months of age, a baby slows down in development, loses interest in play, stops making eye contact, begins to walk clumsily and make repetitive hand movements.

The second phase, known as “rapid destruction,” begins between the ages of one and four.

The child finds it increasingly difficult to communicate and learn, and other brain functions often deteriorate.

Symptoms include an inability to control your hands, sudden fear combined with screaming, unsteadiness, difficulty breathing, difficulty sleeping, slow head growth and digestive problems.

The third stage, the “plateau”, begins between the ages of three and ten.

Limbs become limp, epilepsy may develop, and weight loss and teeth grinding may occur.

However, many parents say that children are less excited and more interested in their surroundings.

The final phase can last for decades. Often develops a severe curvature of the spine – scoliosis – as well as the loss of the ability to walk.

Almost all cases are caused by a mutation in the MECP2 gene, which prevents nerve cells in the brain from working properly.

There is currently no cure and only the symptoms are treated.

According to Rett UK, around three quarters of patients are over the age of 50. The National Institutes of Health says it is not possible to make reliable estimates of life expectancy beyond 40 years.

According to Rettsyndrome.org, data from the Natural History Study found that a girl with Rett has a 100 percent chance of living to age 10, a greater than 75 percent chance of living to age 30, and another as a 50 percent chance to reach the age of 10 the 50th year of life.

But because of Rett’s rarity, very little has been published about its life expectancy.

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