Pharmacists Abbas Kanani and Thorrun Govind have detailed visible signs of syphilis that can be detected on the human body, speaking in an interview with news outlet Metro.
Govind explained that one notable indicator of the infection is a rash appearing on the palms of the hands. She noted that while such a rash typically does not cause itching, it can easily be mistaken for more familiar skin conditions including eczema, psoriasis, or an allergic reaction.

Kanani added that the rash linked to syphilis can also manifest on the soles of the feet. He pointed out that a rash on the feet is easily confused with a fungal skin infection or simple irritation resulting from uncomfortable footwear.
According to Kanani, anyone who discovers an unusual rash on their palms and the bottoms of their feet should take action, particularly if it occurs alongside other unexplained symptoms. He advised getting tested by a medical professional rather than assuming the outbreak is merely a standard skin disorder.
Alternative manifestations and transmission methods
The health experts highlighted that syphilis can manifest in other visible ways beyond skin rashes. They stated that people with the infection may develop sores or ulcers inside the mouth and on the lips, and added that the condition can also cause redness of the eyes.
Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. In medical practice, conditions such as eczema and psoriasis cause localized skin inflammation, while fungal infections like athlete's foot frequently cause peeling or redness on the feet, leading to potential diagnostic confusion when secondary syphilis rashes appear.
In earlier warnings regarding sexual health, sexologists Becky Crappsley-Fox and Annabelle Knight cautioned that sexually transmitted infections are not passed solely through penetrative sexual contact. The sexologists explained that transmission can also occur during oral sex and even through kissing.
Healthcare providers advise individuals who suspect they may have been exposed to an infection or who notice persistent skin and mucosal changes to visit a sexual health clinic or GP surgery for diagnostic testing.
